multiresolution deep cnn (Panoptes Pharma GmbH)
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Multiresolution Deep Cnn, supplied by Panoptes Pharma GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/multiresolution+deep+cnn/multiresolution+deep+cnn/pmc09365068-250-8-12
Average 90 stars, based on 1 article reviews
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1) Product Images from "Machine Learning for Endometrial Cancer Prediction and Prognostication"
Article Title: Machine Learning for Endometrial Cancer Prediction and Prognostication
Journal: Frontiers in Oncology
doi: 10.3389/fonc.2022.852746
Figure Legend Snippet: Working of PANOPTES, a multiresolution deep convolutional neural network (CNN). In this trained model generated through the CNN algorithm, pathological images were used to predict the gene mutations and histological and molecular subtypes of EC. PANOPTES ML models using multiresolution architecture can classify histological subtypes of EC, molecular subtypes, and critical mutations (loss or gain of functions) with decent performance based on H&E (hematoxylin and eosin), IHC (immunohistochemistry), and IF (immunofluorescence) images. Also, some data can be accessed from the input CEL files. Predicated on the input, CNN models identify subtypes and mutations in EC. Multiresolution CNN models outperform single-resolution CNN models on the visual patterns. CNN models would incorporate human interpretable tumor characteristics according to feature extraction. Tumor grade identifies the molecular subtype and classifies into high-risk or low-risk cohorts from endometrioid histology samples to capture characteristics of varied sizes on the H&E, IHC, and IF slides, which is similar to a human operator pathological evaluation. Unlike traditional CNN architectures, Panoptes’ input is a group of three tiles from the same region on the image slide rather than one tile. CEL file: differential expression profile generated by Affymetrix DNA microarray-based software analysis.
Techniques Used: Generated, Immunohistochemistry, Immunofluorescence, Extraction, Quantitative Proteomics, Microarray, Software
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